In What Organelle Does Cellular Respiration Take Place?

Cellular Respiration Glycolysis, Citric Acid Cycle
Cellular Respiration Glycolysis, Citric Acid Cycle from biology.about.com

Introduction

Cellular respiration is a vital process that occurs in living organisms to produce energy in the form of ATP (adenosine triphosphate). It is a complex metabolic pathway that involves the breakdown of glucose and other organic molecules to release energy. In eukaryotic cells, cellular respiration primarily takes place in the mitochondria, which are double-membraned organelles responsible for energy production.

The Mitochondria: Powerhouses of the Cell

The mitochondria are often referred to as the “powerhouses” of the cell because they generate the majority of ATP through cellular respiration. These bean-shaped organelles have an outer membrane and an inner membrane with numerous folds called cristae. The inner membrane encloses the mitochondrial matrix, which contains enzymes and other molecules involved in cellular respiration.

Glycolysis: The First Step

The process of cellular respiration starts with glycolysis, which takes place in the cytoplasm of the cell. During glycolysis, a molecule of glucose is broken down into two molecules of pyruvate. This process generates a small amount of ATP and NADH, a coenzyme that carries electrons to the next stage of cellular respiration.

The Krebs Cycle: Generating Energy

After glycolysis, the pyruvate molecules move into the mitochondria, where the Krebs cycle, also known as the citric acid cycle, takes place. This cycle completes the breakdown of glucose, releasing carbon dioxide and producing ATP, NADH, and FADH2, another electron carrier.

Electron Transport Chain: The Final Step

The last stage of cellular respiration is the electron transport chain, which occurs in the inner mitochondrial membrane. The NADH and FADH2 generated in previous steps donate their electrons to the electron transport chain, creating a flow of electrons. This process generates a large amount of ATP through oxidative phosphorylation.

Summary: Mitochondria and Cellular Respiration

In summary, cellular respiration primarily takes place in the mitochondria of eukaryotic cells. Through a series of metabolic reactions, including glycolysis, the Krebs cycle, and the electron transport chain, cells break down glucose and other organic molecules to produce ATP. The mitochondria play a crucial role in energy production and are essential for the functioning of all living organisms.

Conclusion

Understanding the organelle where cellular respiration takes place is important for comprehending the fundamental processes that sustain life. The mitochondria, with their intricate structure and specialized enzymes, are the key players in this energy-generating process. By harnessing the power of cellular respiration, organisms can carry out various activities, from basic cellular functions to complex tasks. This knowledge helps scientists develop a deeper understanding of diseases related to mitochondrial dysfunction and discover potential therapeutic interventions.

Sources:

1. Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P. (2002). Molecular Biology of the Cell, 4th edition. Garland Science.

2. Campbell, N. A., & Reece, J. B. (2002). Biology, 6th edition. Benjamin Cummings.